Extramural Research

The NIAAA extramural research portfolio is wide-ranging and varied. 


NIAAA determines its research priorities through guidance from:

  • National Advisory Council and its subcommittees
  • Input from researchers in the field
  • Input from NIAAA research staff
  • Input from liaison groups
  • Important themes at national and international meetings and conferences
  • NIAAA Strategic Plan
  • NIAAA Health Disparities Strategic Plan
  • Congressional legislation and reports


Examples of research initiatives we have invested in recently include:



Long-term, Community-Based Prevention of Alcohol Problems at Specific Life Stages



Basic Research on Medications Development for Alcohol-Use Disorders

Advancing Behavioral Therapies for Alcoholism



Genetic Studies of Vulnerability to Alcohol

Behavioral and Genetic Risk Factors for Alcoholism



Identifying the Neuroscientific Basis of Alcohol-Related Behaviors


Health Effects

Mechanisms and Markers of Alcohol-Induced Organ Damage and Organ Protection

Multi-site, Collaborative Initiative on Fetal Alcohol Syndrome


Health Disparities

Disparities in Adverse and Beneficial Effects of Alcohol



Women, HIV/AIDS, and Alcohol


Intramural Research

Intramural research is conducted in the Division of Intramural Clinical and Biological Research.

The NIAAA intramural research program investigates how to prevent, diagnose, and treat alcohol-related problems through basic and applied research, as well as by operating a clinical research facility.


Research areas include:

  • Studies on the cellular/molecular basis of alcohol-related disease
  • Animal studies in rodents and non-human primates
  • Human studies of the genetics and epidemiology of alcoholism and co-morbidities
  • Validation of novel molecular targets for alcohol use disorders


Intramural laboratories are:

  • Laboratory of Behavioral and Genomic Neuroscience
  • Laboratory of Clinical and Translational Studies
  • Laboratory of Epidemiology and Biometry
  • Laboratory for Integrative Neuroscience
  • Laboratory of Liver Diseases
  • Laboratory of Membrane Biochemistry and Biophysics
  • Laboratory of Metabolic Control
  • Laboratory of Molecular Physiology
  • Laboratory of Molecular Signaling
  • Laboratory of Neurogenetics
  • Laboratory of Neuroimaging
  • Laboratory of Physiologic Studies
  • Chemical Biology Research Branch (joint lab with NIDA)


Our approach to research is multidisciplinary, and so our researchers collaborate with each other, as well as with researchers in other NIH Institutes and Centers, and external institutions.


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