8:30 am -  Welcome / Introduction

Session I: Negative Affect Associated with Alcohol Abstinence
 
8:50 am -  Compulsive alcohol seeking driven by negative emotional states associated with alcohol  abstinence
                   George Koob, Ph.D., Professor and Chair of the Committee on the Neurobiology of Addictive  Disorders, the Scripps Research  Institute

9:20 am -  Disrupted stress-related mPFC/ACC activity jeopardizes alcohol recovery 
                   Rajita Sinha, Ph.D., Professor of Psychiatry and Director of Interdisciplinary Stress Center, Yale University

9:50 am -  Glia-neuron communication in sleep disorders associated with alcoholism
                   Mahesh Thakkar, Ph.D., Associate Professor of Neurology, School of Medicine, University of  Missouri Health System

10:20 am -  Break

Session II:  Cognitive Function Deficit and Recovery

10:35 am -  Persistent increases in TLR signaling and reversal learning deficits in abstinence 
                     Fulton Crews, Ph.D., Professor, Department of Pharmacology, Director, Bowles Center for  Alcohol Studies, University of North Carolina

11:05 am -  Plasticity of the mPFC and protracted deficit in executive 
                     Judson Chandler, Ph.D., Professor, Center for Drug and Alcohol Programs, Medical University of  South Carolina

11:35 am -  Recovery of cognitive deficit in alcoholism
                     Adolf Pfefferbaum, M.D., Director, Neuroscience Program, Center for Health Sciences, SRI  International

12:05 am -  Lunch Break
 
Session III: Neuroadaptation During Abstinence
 
1:15 pm - Genetic influences and gene expression changes associated with alcohol dependence, withdrawal, and relapse drinking
                  Howard Becker, Ph.D., Professor, Departments of Psychiatry and Neuroscience, Director,  Charleston Alcohol Research Center, Medical University of South Carolina
 
1:45 pm - Neuroadaptation of the striatum associated with relapse drinking during early and protracted abstinence
                  David Lovinger, Ph.D., Senior Investigator and the Chief of the Laboratory for Integrative Neuroscience, NIAAA

2:15 pm - Promoting abstinence by decreasing the impact of drug-associated memories through reconsolidation blockade
                  Barry Everitt, Sc D, FRS, F Med Sci, Professor, Department of Psychology, University of Cambridge

2:45 pm - Break

Session IV: Neuromechanisms of Treatment

3:00 pm - Relationship between cortical gliogenesis and alcohol use disorders: new avenues for novel therapies
                  Chittra Mandyam, Ph.D., Associate Professor, Committee on the Neurobiology of Addictive Disorders, the Scripps Research Institute

3:30 pm - Resting-state synchrony: a potential target for a neurofeedback treatment of alcoholism
                  George Fein, Ph.D., Senior Scientists, President, Neurobehavioral Research Inc.

4:00 pm - Using neuroimaging approaches to investigate treatment mechanisms
                   Marc N Potenza PhD, MD, Professor of Psychiatry, Child Study and Neurobiology, Yale University

4:30 pm   Panel Discussion

Panelists include all the speakers and Drs. Kathy Grant, Adron Harris, Patricia Janak, Tom Kash, Dieter Meyehoff, Marisa Roberto, Dorit Ron, and Edith Sullivan.