Alcohol and its metabolites suppress human brain function and affect behavior, however, little is known about the neurological processes that mediate the action of EtOH metabolites in the brain. My group is implementing in vitro and in vivo  techniques to explore the molecular and cellular mechanisms underlying alcohol metabolism and intoxication in the brain. We are also interested in the role of glycinergic transmission in cannabinoid and opioid-induced cellular and behavioral effects in the brain.