The effectiveness of an experimental treatment for alcoholism depends on the genetic makeup of individuals who receive it, according to a new study supported by the National Institute on Alcohol Abuse and Alcoholism (NIAAA), part of the National Institutes of Health. A report of the findings appears online in the American Journal of Psychiatry. “This study represents an important milestone...
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Girls who suffered childhood sexual abuse are more likely to develop alcoholism later in life if they possess a particular variant of a gene involved in the body’s response to stress, according to a new study led by researchers at the National Institute on Alcohol Abuse and Alcoholism (NIAAA), part of the National Institutes of Health (NIH). The new finding...
NIH-funded study says five-marker genotype panel can guide ondansetron use An experimental treatment for alcohol dependence works better in individuals who possess specific combinations of genes that regulate the function and binding of serotonin, a brain chemical affected by the treatment, according to a study supported by the National Institutes of Health. A report of the finding appears online in...
NIH-funded study provides hope for better disease prediction. What : An international team of scientists supported by the National Institute on Alcohol Abuse and Alcoholism (NIAAA), part of the NIH, has identified a novel association between the gene FAF2 and a reduced risk for alcohol-associated liver cirrhosis (ALC) in people who drink heavily. Also confirmed by the study were four...
Many children adversely affected by maternal drinking during pregnancy cannot be identified early in life using current diagnostic criteria for fetal alcohol spectrum disorder (FASD). In the current study, conducted with pregnant rats, researchers examined whether ethanol-induced alterations in placental gene expression may be useful as diagnostic indicators of maternal drinking during pregnancy and as a prognostic indicators of risk...
Scientists at the National Institutes of Health’s (NIH) National Institute on Alcohol Abuse and Alcoholism (NIAAA) have identified a previously unknown gene variant that doubles an individual’s risk for obsessive-compulsive disorder (OCD). The new functional variant, or allele, is a component of the serotonin transporter gene ( SERT), site of action for the selective serotonin reuptake inhibitors (SSRIs) that are...
CONTENTS A. Reauthorization Legislation and Budget B. Director's Activities C. NIAAA Staff and Organization D. NIAAA Research Programs E. Scientific Meetings F. Outreach G. Multi-Media Products from NIAAA A. Reauthorization Legislation and Budget NIH Reform Act In December, Congress passed a reauthorization bill for NIH, the third ever omnibus reauthorization for the agency. Previous omnibus reauthorizations were enacted in 1993...
The National Advisory Council on Alcohol Abuse and Alcoholism (NIAAA) convened for its 132nd meeting at 5:00 p.m. on February 6, 2013, at the Fishers Lane Conference Center in Rockville, Maryland, in closed session for a review of grant applications, a special Council review, and a Merit Award nomination/extension. The meeting recessed at 6:50 p.m. Dr. Abraham Bautista, Director, Office...
A variant of a gene involved in communication among brain cells has a direct influence on alcohol consumption in mice, according to a new study by scientists supported by the National Institute on Alcohol Abuse and Alcoholism (NIAAA), part of the National Institutes of Health (NIH), and the U.S. Army. Scientists do not know yet whether a similar gene variant...
According to the results of a recent NIAAA-funded animal study, carrying a gene variant that affects the release of a specific brain protein may increase the risk of developing an alcohol use disorder. The protein, brain-derived neurotrophic factor (BDNF), affects the survival of existing neurons and the growth of new neurons and synapses, the junctures through which cell-to-cell communication occurs...
A. Legislation , Budget, and Policy Budget Update FY 2010 In FY 2010, the NIAAA obligated $462.1 million in appropriated money. As part of the NIH Director’s one-percent transfer authority and consistent with FY 2009 action, $704 thousand was transferred from NIAAA for the Genes and Environment Initiative (GEI). NIAAA awarded 706 research project grants (RPGs), including 189 competing awards...
The National Advisory Council on Alcohol Abuse and Alcoholism (NIAAA) convened for its 134th meeting at 5:30 p.m. on September 18, 2013, at the Fishers Lane Conference Center in Rockville, Maryland. The Council met in closed session for a review of grant applications and a Merit Award extension. The meeting recessed at 6:37 p.m. Dr. Abraham Bautista, Director, Office of...
CONTENTS A. Legislation, Budget, and Policy B. Director’s Activities C. NIAAA Staff and Organization D. Multi-Media Products from NIAAA E. News Media Interactions F. NIAAA Program Announcement and Request for Applications Information G. NIAAA Research Programs A. Legislation, Budget, and Policy Budget Update FY 2011 Full Year Continuing Resolution After a series of temporary funding measures, on April 15, 2011...
CONTENTS A. Legislation, Budget, and Policy B. Director’s Activities C. NIAAA Staff and Organization D. Multi-Media Products From NIAAA E. Outreach F. News Media Interactions G. What’s Ahead H. NIAAA Program Announcement and Request for Applications Information I. NIAAA Research Programs J. Scientific Meetings A. Legislation, Budget, and Policy Budget Update FY2009 American Recovery & Reinvestment Act 2009 (ARRA) Stimulus...