Remarkable progress has been made in the fight against HIV/AIDS since the first annual World AIDS Day was commemorated 26 years ago. Yet, we are still far from achieving our goal of a world without AIDS.

Statement by 
Anthony S. Fauci, M.D. Director, National Institute of Allergy and Infectious Diseases
Jack Whitescarver, Ph.D., Director, NIH Office of AIDS Research
Francis S. Collins, M.D., Ph.D, NIH Director

In 2013, more than 2 million people globally became newly infected with HIV, and 1.5 million people died from AIDS-related causes. The number of new HIV infections and AIDS-related deaths has dropped by more than one-third in the past decade largely because of advances in HIV prevention and greater access to antiretroviral therapy. However, far too many adults and children continue to become HIV-infected and die from the effects of the virus, including here in the United States. On World AIDS Day, the National Institutes of Health reaffirms its commitment to finding new tools for preventing HIV infection (including a vaccine), improved treatments, and, ultimately, a cure....

Integrating HIV/AIDS and Alcohol Research [PDF]
  Kendall J. Bryant, Steve Nelson, R. Scott Braithwaite and Deidra Roach

• HIV Risk and the Alcohol Environment: Advancing an Ecological Epidemiology for HIV/AIDS [PDF]
  Richard Scribner, Katherine P. Theall, Neal Simonsen and William Robinson

• Social and Structural HIV Prevention in Alcohol-Serving Establishments: Review of International Interventions Across Populations [PDF]
  Seth C. Kalichman

• Biomedical Approaches to HIV Prevention [PDF]
  Kenneth H. Mayer, Margie Skeer and Matthew J. Mimiaga

• Alcohol’s Role in HIV Transmission and Disease Progression [PDF]
  Ivona Pandrea, Kyle I. Happel, Angela M. Amedee, Gregory J. Bagby and Steve Nelson

• HIV/AIDS, Comorbidity, and Alcohol: Can We Make a Difference? [PDF]
  Amy Justice, Lynn Sullivan and David Fiellin

• Interventions Targeting HIV-Infected Risky Drinkers: Drops in the Bottle [PDF]
  Jeffrey H. Samet and Alexander Y. Walley

• Influence of Alcohol Consumption on Adherence to and Toxicity of Antiretroviral Therapy and Survival [PDF]
  R. Scott Braithwaite and Kendall J. Bryant

Special Section: Modeling HIV and Alcohol’s Effects 

• Focus on the Lung [PDF]
  David Quintero and David M. Guidot

• Focus on the Liver: Alcohol Use, Highly Active Antiretroviral Therapy, and Liver Disease in HIV-Infected Patients [PDF]
  Shirish Barve, Rama Kapoor, Akshata Moghe, Julio A. Ramirez, John W. Eaton, Leila Gobejishvili, Swati Joshi-Barve and Craig J. McClain

• Focus on the Heart: Alcohol Consumption, HIV Infection, and Cardiovascular Disease [PDF]
  Matthew S. Freiberg and Kevin L. Kraemer

• Focus on the Brain: HIV Infection and Alcoholism: Comorbidity Effects on Brain Structure and Function [PDF]
  Margaret J. Rosenbloom, Edith V. Sullivan and Adolf Pfefferbaum