Promotes and supports applied, translational, and methodological research on the epidemiology and prevention of hazardous alcohol consumption and related behaviors, alcohol-related mortality and morbidity, and other alcohol-related problems and consequences.


Supports basic and clinical research studies to identify the molecular pathways through which alcohol causes organ and tissue damage, with the goal of identifying targets for drug discovery to prevent or treat alcohol-related disorders.


Focuses on pharmacological treatment for alcohol use disorder (AUD) and supports clinical research programs.


Promotes research on ways in which neuronal and behavioral systems are influenced by genetic, developmental, and environmental factors in conjunction with alcohol exposure to engender alcohol abuse and alcoholism.


Supports research to better understand the natural history of excessive drinking and alcohol use disorders and factors associated with positive change.

Responsible for extramural grant and contract review, the management of chartered initial review groups and special emphasis panels, and all grants management activities. OEA also manages the Committee Management Office—responsible for advisory council activities and nominations to advisory and review panels—and provides advice to the Institute's senior leadership on matters that concern FACA (Federal Advisory Committee Act) and non-FACA meetings.