Dr. Murray joined the NIAAA after a long career as an intramural scientist in the National Institute of Neurological Disorders and Stroke where he explored treatment strategies for lysosomal storage disorders, primarily Gaucher disease and Fabry disease. Dr. Murray applied his experience in biochemistry, lipid chemistry, cell and molecular biology and in animal models to studies of enzyme and gene replacement therapy for these disorders leading to the successful implementation of Enzyme Replacement Therapy. In the NIAAA, Dr. Murray and the staff of the Division perform a variety of duties in program administration and design and in the review and management of a portfolio of grants related to alcohol, its metabolism and the downstream influences on health. Dr. Murray’s current focus is on alcohol-induced organ and tissue damage with a particular interest in alcohol and cancer. Dr. Murray served as the Acting Director of the Division of Metabolism and Health Effects from 2012 to 2016.