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NIAAA Staff Profile


National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Program Director

Andras Orosz, Ph.D.

Andras Orsoz

6700B Rockledge Drive
Room 1237
Bethesda, MD 20892-6902

Focus Area

aging; Alcohol-associated Liver Disease; animal models; cardiovascular disease; cell organelles; epigenetics; metabolism; Protein homeostasis (Proteostasis); transcription regulation

Biographical Summary

Dr. Orosz is a Program Director in the Division of Metabolism and Health Effects at NIAAA since 2008. He obtained his Ph.D. from the Attila Jozsef University in Szeged, Hungary where he studied the transcriptional termination mechanism of the E. coli ribosomal RNA operon rrnB. He received postdoctoral training at NCI, Bethesda investigating the eukaryotic transcriptional master stress regulator Heat Shock Factor (HSF) in Drosophila. Subsequently, as a Research Fellow at the Laboratory of Metabolism, NCI, Bethesda he examined the role of basic leucine zipper transcription factors in lipoatrophic diabetes, carcinogenesis and addiction. Before joining NIAAA Dr. Orosz has been a research instructor at the Cardiology Division at the University of Utah Health Sciences Center in Salt Lake City, Utah where his research focused on elucidating the cardioprotective functions of Heat Shock Proteins (HSPs) and Heat Shock Factor 1 (HSF1). Dr. Orosz has a diverse portfolio that overarches a broad range of alcohol induced pathologies including the cardiovascular system, proteostasis (protein homeostasis) pathways, alcoholic liver disease, epigenetics, mitochondrial dysfunction and apoptosis, and identification and validation of alcohol biomarker signatures.

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