National Institute on Alcohol Abuse and Alcoholism (NIAAA)
With nearly 29.5 million adults (18 years or older) in the United States with an alcohol use disorder (AUD) and an annual total economic cost of $249 billion, there is a clear need for more interventions to treat AUDs. More treatment options can help minimize the negative consequences felt by individuals with AUD, their families, workplaces, and society as a...
Andras Orosz, Ph.D. with contributions from: Changhai Cui, Ph.D., I-Jen Castle, Ph.D., and Deidra Roach, M.D. Alcohol and Aging (R01, R21; New concept addressing a priority area of the 2017-2021 NIAAA Strategic Plan) Purpose The purpose of this Notice of Special Interest (NOSI) is to promote research to improve our understanding of the effects of alcohol consumption on aging across...
Communities can decrease alcohol-related fatal crashes by providing better access to substance abuse treatment while reducing the availability of alcohol in the community, according to a new study supported by the National Institute on Alcohol Abuse and Alcoholism (NIAAA), part of the National Institutes of Health (NIH). A report of the study appears in the April, 2005 issue of the...
Results from a recent NIAAA study suggest that the medication ibudilast may be viable as a potential treatment for alcohol dependence. Ibudilast, an anti-inflammatory medication that acts as a non-selective phosphodiesterase inhibitor, reduces alcohol drinking and relapse in alcohol-preferring P rats, high-alcohol drinking HAD1 rats, and in mice made dependent on alcohol through cycles of alcohol vapor exposure. Neuroinflammatory signaling...
NIH researchers seek to expand treatment options A smoking-cessation medication may be a viable option for the treatment of alcohol dependence, according to a study by scientists at the National Institutes of Health. The study found that varenicline (marketed under the name Chantix), approved in 2006 to help people stop smoking, significantly reduced alcohol consumption and craving among people who...