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National Institute on Alcohol Abuse and Alcoholism (NIAAA)

News Release

Heart medication shows potential as treatment for alcohol use disorder
For Release
A medication for heart problems and high blood pressure may also be effective for treating alcohol use disorder, according to a new study by researchers at the National Institutes of Health and their colleagues. The study presents converging evidence from experiments in mice and rats, as well as a cohort study in humans, suggesting that the medication, spironolactone, may play...
FY 2006 President's Budget Request for NIAAA - Director's Statement Before the House and Senate Appropriations Subcommittees

Statement by Ting-Kai Li, M.D., Director National Institute on Alcohol Abuse and Alcoholism National Institutes of Health Department of Health and Human Services Mr. Chairman and Members of the Committee: I am pleased to present the Fiscal Year (FY) 2006 President's budget request for the National Institute on Alcohol Abuse and Alcoholism (NIAAA). The FY 2006 budget includes $440,333,000, which...

Semaglutide shows promise as a potential alcohol use disorder medication
This article was first published in NIAAA Spectrum Volume 16, Issue 1. Intramural scientists at the National Institute on Alcohol Abuse and Alcoholism (NIAAA) and the National Institute on Drug Abuse (NIDA), and collaborators from The Scripps Research Institute, found that semaglutide reduces alcohol consumption and binge-like drinking in a rodent model of alcohol misuse . Published in the June...

News Release

NIAAA Launches COMBINE Clinical Trial - Eleven universities to test behavioral and pharmacologic treatments for alcoholism
For Release

The National Institute on Alcohol Abuse and Alcoholism (NIAAA) today announces the start of Combining Medications and Behavioral Interventions (COMBINE), a nationwide study that targets persons with the diagnosis alcohol dependence, commonly known as alcoholism. COMBINE is the first national study to evaluate the effectiveness of behavioral treatments alone and in combination with medications. It begins at a time when...

News Release

Gene Variant Predicts Medication Response in Patients with Alcohol Dependence
For Release

Patients with a certain gene variant drank less and experienced better overall clinical outcomes than patients without the variant while taking the medication naltrexone, according to an analysis of participants in the National Institutes of Health's 2001-2004 COMBINE (Combined Pharmacotherapies and Behavioral Interventions for Alcohol Dependence) Study. About 87 percent of patients with the variant who received naltrexone. experienced good...

Current Studies on Prevention of Alcohol Use in Pregnancy

April 23-24, 1998 • Ramada Inn • Bethesda, Maryland Abstracts Activities of the Center for Addiction Research and Education Michael F. Fleming, M.D., M.P.H. From the Department of Family Medicine, University of Wisconsin, Madison, Wisconsin The University of Wisconsin Center for Addiction Research and Education (CARE) has a number of projects that focus on the prevention of alcohol problems in...

Alcohol Policy

General Alcohol Policy A combination of Federal, State, and local laws help shape the role alcohol plays in the United States, including how we: Manufacture alcohol Sell alcohol Decide who can drink alcohol Respond to alcohol-related problems The primary Federal law governing alcohol policy is the 21st Amendment, which repealed national prohibition. It also gives individual States control over: Whether...

Alcohol and HIV/AIDS - Comorbidities, Coinfections, and Complications Research: Intervention and Cross-Cutting Foundational Research
Kendall Bryant, Ph.D. Purpose The future Notice of Funding Opportunity (NOFO, a reissue of RFA AA 16-001 ) will solicit applications for human studies that will advance operations or implementation research in the context of alcohol and HIV/AIDS by facilitating the development of: (1) broader systems approaches for monitoring complex HIV and alcohol-related morbidity and mortality, and (2) interventions to...

Directors Reports

NIAAA Directors Report on Institute Activities to the 135th Meeting of the National Advisory Council on Alcohol Abuse and Alcoholism

Table of Contents NIAAA WELCOMES NEW DIRECTOR NIAAA BUDGET DIRECTOR’S ACTIVITIES STAFF TRANSITIONS & AWARDS HONORS & AWARDS NEW RFA’S/PA’S NIAAA COMMUNICATIONS & MEDIA COVERAGE SELECT NIAAA STAFF ACTIVITIES WHAT’S AHEAD NIAAA RESEARCH HIGHLIGHTS NIAAA Welcomes New Director On January 27, 2014, George F. Koob, Ph.D., joined NIH as Director of the National Institute on Alcohol Abuse and Alcoholism. Dr...
15-AA-0127 - Epi-Genetic Modulators of Fear Extinction in Alcohol Dependence
DO YOU DRINK ALCOHOL TO DEAL WITH STRESS? Doctors at the National Institutes of Health (NIH) seek volunteers between 21-65 year of age who drink heavily and/or had a stressful childhood to participate in a study looking at the effect of alcohol abuse and early life stress on the ability to feel calm. All study-related tests and procedures are provided...
NIAAA Director's Statement for the Record on NIAAA FY 2015 Budget Request, Senate Subcommittee on Labor-HHS-Education Appropriations

Mr. Chairman and Members of the Committee: As the new Director of the National Institute on Alcohol Abuse and Alcoholism (NIAAA) of the National Institutes of Health (NIH), I am pleased to present the President’s Budget request for the Institute. The fiscal year (FY) 2015 NIAAA budget request of $446,017,000 reflects an increase of $606,000 over the comparable FY 2014...

Directors Reports

NIAAA Director's Report on Institute Activities to the 150th Meeting of the National Advisory Council on Alcohol Abuse and Alcoholism

Table of Contents NIAAA BUDGET IN MEMORIAM COLLABORATIVE RESEARCH ON ADDICTION AT NIH UPDATE DIRECTOR'S ACTIVITIES STAFF TRANSITIONS HONORS AND AWARDS NEW REQUESTS FOR APPLICATIONS AND PROGRAM ANNOUNCEMENTS NOTABLE NIAAA STAFF ACTIVITIES WHAT'S AHEAD NIH RESEARCH HIGHLIGHTS NIAAA COMMUNICATIONS ACTIVITIES NIAAA BUDGET Fiscal Year (FY) 2018 The National Institute on Alcohol Abuse and Alcoholism (NIAAA) closed FY 2018 on September...
The Right to Resist
When middle schoolers face pressure to do things that are not right or good for them, they have the right to resist. They have the right to say no, the right not to give a reason why, and the right to just walk away from a situation. Resisting pressure can be hard for some people. Why? They… Are afraid of...

News Release

NIH begins clinical trial of new medication for alcohol use disorder
For Release

A clinical trial investigating a potential treatment for alcohol use disorder (AUD) was announced by the National Institute on Alcohol Abuse and Alcoholism (NIAAA). The study will assess the safety and efficacy of gabapentin enacarbil (HORIZANT) in extended-release tablets for treating moderate to severe AUD. NIAAA is part of the National Institutes of Health. Gabapentin is already widely prescribed to...

Advisory Council Minutes

National Advisory Council Meeting - September 16-17, 2009

Summary of the 122nd Meeting September 16-17, 2009 The National Advisory Council on Alcohol Abuse and Alcoholism (NIAAA) convened for its 122nd meeting at 5:30 p.m. on September 16, 2009, at the Fishers Lane Conference Center in Rockville, Maryland, in a closed session. Dr. Abraham Bautista presided over the closed review of grant applications and Merit Award nominations. Dr. Kenneth...

Directors Reports

NIAAA Director's Report on Institute Activities to the 131st Meeting of the National Advisory Council on Alcohol Abuse and Alcoholism

Table of Contents NIAAA DIRECTOR’S NOTE NIAAA BUDGET DIRECTOR’S ACTIVITIES STAFF TRANSITIONS STAFF AWARDS NEW RFA’S/PA’S NIAAA COMMUNICATIONS & MEDIA COVERAGE SELECT NIAAA STAFF ACTIVITIES NEW AND UPCOMING PUBLICATIONS WHAT’S AHEAD NIAAA RESEARCH HIGHLIGHTS Director’s Note Fall Update – NIAAA’s work combatting the harms of college drinking As fall begins and students return to college campuses across the country, we...

News Release

Alcohol Researchers Prove Brief Intervention Successful In Older Problem Drinkers
For Release

A study reported in the Journal of Family Practice (Volume 48, Number 5) shows that brief intervention can reduce alcohol consumption in problem drinkers aged 65 years and older. Project GOAL (Guiding Older Adult Lifestyles) is the first U.S. randomized controlled clinical trial to test the effectiveness of brief counseling by community-based primary care physicians in older problem drinkers. "Following...

Project MATCH Monograph Series
Series Editor: Margaret E. Mattson, Ph.D. It has been more than a decade since the eighth volume of the Project MATCH Monograph Series was published. The initial purpose of this series of manuals was to disseminate methodology developed by the investigators of the multisite clinical trial Project MATCH (1990–1997), an initiative funded by the National Institute on Alcohol Abuse and...

Directors Reports

NIAAA Director's Report on Institute Activities to the 133rd Meeting of the National Advisory Council on Alcohol Abuse and Alcoholism

Table of Contents NIAAA DIRECTOR’S NOTE NIAAA BUDGET DIRECTOR’S ACTIVITIES STAFF TRANSITIONS STAFF HONORS NEW RFA’S/PA’S NIAAA COMMUNICATIONS & MEDIA COVERAGE NOTABLE NIAAA STAFF ACTIVITIES NEW & UPCOMING PUBLICATIONS NOTABLE EVENTS WHAT’S AHEAD NIAAA RESEARCH HIGHLIGHTS Director’s Note Advancing Treatment for Alcohol Dependence Earlier in June, we announced an exciting research finding in the treatment field -- varenicline, a smoking-cessation...
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