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National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Ibudilast reduces alcohol drinking in multiple animal models of alcohol dependence

Results from a recent NIAAA study suggest that the medication ibudilast may be viable as a potential treatment for alcohol dependence. Ibudilast, an anti-inflammatory medication that acts as a non-selective phosphodiesterase inhibitor, reduces alcohol drinking and relapse in alcohol-preferring P rats, high-alcohol drinking HAD1 rats, and in mice made dependent on alcohol through cycles of alcohol vapor exposure. Neuroinflammatory signaling...

Event

Webinar: Depression, Alcohol Use & Mental Health
Friday, November 2, 2018, 11:00 am EDT

Presentation title : Depression's got a hold of me: Gender differences and generational trends in alcohol use and mental health among U.S. adolescents and adults Date : Friday, November 2, 2018, 11:00 a.m. – 12:00 p.m. Speaker: Katherine Keyes, Ph.D. Join WebEx Meeting : https://bit.ly/2CSu4Jc Call-in toll number (US/Canada ): 1-650-479-3208 Meeting Number (access code) : 628-802-815 Meeting Password...

Laboratory on Human Psychopharmacology (HP)

What we do Alcohol use disorder (AUD) has a tremendous negative individual and global impact, and there is an urgent need to understand its etiology and to advance treatment for this devastating illness. Research on the clinical pharmacology of alcohol is necessary to explain how variability in alcohol response affects the risk of developing AUD. The premise underlying the research...

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