National Institute on Alcohol Abuse and Alcoholism (NIAAA)
An estimated 17.6 million American adults (8.5 percent) meet standard diagnostic criteria for an alcohol use disorder * and approximately 4.2 million (2 percent) meet criteria for a drug use disorder. Overall, about one-tenth (9.4 percent) of American adults, or 19.4 million persons, meet clinical criteria for a substance use disorder--either an alcohol or drug use disorder or both--according to...
The National Institute on Alcohol Abuse and Alcoholism today released the first report from its National Longitudinal Alcohol Epidemiologic Survey (NLAES), including the most precise estimates to date of alcohol abuse and dependence among U.S. adults. The figures are reported by Bridget F. Grant, Ph.D., Ph.D., and colleagues in the current issue (Vol. 18, No. 3) of Alcohol Health &...
Statement by Enoch Gordis, M.D., Director National Institute on Alcohol Abuse and Alcoholism National Institutes of Health Department of Health and Human Services March 4, 1997 I am pleased to be here with you today to discuss the many scientific advances and research opportunities at the National Institute on Alcohol Abuse and Alcoholism (NIAAA). The NIAAA is the foremost Federal...
DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Statement by Enoch Gordis, M.D., Director National Institute on Alcohol Abuse and Alcoholism March 4, 1997 Formal statement before the House Committe on Appropriations Subcommittee on Labor, Health and Human Services, Education and Related Agencies, Tuesday, March 4, 1997. I am pleased to be here with you today to discuss...
Pretreating transplanted livers with the immune molecule interleukin-6 (IL-6) dramatically increased survival of rats receiving organs with fatty degeneration—a common condition in humans that typically reduces transplant viability. The results suggest a means of making it possible to use a higher percentage of available donor livers for transplantation in humans. With over three times as many Americans needing transplants as...
A team of NIH-supported researchers today report that alcohol increases replication of the hepatitis C virus (HCV) in human cells and, by so doing, may contribute to the rapid course of HCV infection. The researchers tested the actions of alcohol in HCV replicon--viral HCV-ribonucleic acid or HCV-RNAs that, when introduced into human liver cell lines, replicate to high levels. In...
The National Advisory Council on Alcohol Abuse and Alcoholism (NIAAA) convened for its 134th meeting at 5:30 p.m. on September 18, 2013, at the Fishers Lane Conference Center in Rockville, Maryland. The Council met in closed session for a review of grant applications and a Merit Award extension. The meeting recessed at 6:37 p.m. Dr. Abraham Bautista, Director, Office of...
An article in today’s Federation of American Societies for Experimental Biology (FASEB) Journal (Chen, S; Wilkemeyer, M; Sulik, K; and Charness, M. Octanol antagonism of ethanol teratogenesis, FASEB J. 10.1096/fj00-08620fje and Volume 15, Number 9, July 2001) reports that the long-chain alcohol 1-octanol successfully blocks a mechanism leading to fetal alcohol syndrome (FAS). Viewed as paradoxical because it is the...
Washington, D.C. Theodore Reich, M.D., Department of Psychiatry, Washington University School of Medicine, St. Louis, and colleagues at that university and others in the NIAAA-supported Collaborative Study on the Genetics of Alcoholism (COGA) report in this month's Neuropsychiatric Genetics (Volume 81, Number 3) highly suggestive evidence on chromosomes 1 and 7 and more modest evidence on chromosome 2 for linkage...
Mission Statement: The mission of the Laboratory of Liver Diseases is to investigate the immunological aspects and molecular pathogenesis of alcoholic and nonalcoholic fatty liver diseases, and to explore novel therapeutic targets for the treatment of these disorders. Bin Gao MD. , PhD, Chief Laboratory of Liver Diseases National Institute on Alcohol Abuse and Alcoholism National Institutes of Health 5625...