NIH Independent Research Scholar, Chief, Unit on Motivation and Arousal

Andrew Kesner, Ph.D.

My overarching scientific interests are in the neural mechanisms of motivated behavior and the maladaptations of these mechanisms that give rise to psychiatric disorders like depression, anxiety, and addiction. An often-overlooked component of these psychiatric illnesses is poor sleep quality or disrupted sleep. In the Unit on Motivation and Arousal, we use multiple approaches including in-vivo single-unit and ECoG/EMG recording, optogenetics, chemogenetics, and in-vivo photometric imaging to study the neural and behavioral manifestations of sleep disruption occurring when mice experience withdrawal from THC, the major psychedelic component of cannabis.