National Institute on Alcohol Abuse and Alcoholism (NIAAA)
About the Underage Drinking Research Initiative The Underage Drinking Research Initiative (UDRI) is a key program of NIAAA. The goal of this initiative is to better understand the factors that compel youth to begin drinking, continue drinking, and progress to harmful use, abuse, and dependence. We seek to understand and address underage drinking within the context of overall development, and...
NIAAA’s major initiatives seek to address alcohol-related issues across the lifespan. Our aim is to reduce the tremendous burden of illness resulting from the misuse of alcohol by: Preventing children and adolescents from beginning and continuing to drink alcohol Offering effective intervention for problem alcohol use at all ages To accomplish this, we support research in areas ranging from basic...
Treatment for alcohol use disorder (AUD) includes behavioral treatments such as mutual support groups and individual therapy, as well as pharmaceutical treatments. Often these are used in combination. Currently, there are three Food and Drug Administration (FDA)-approved medications for the treatment of AUD: Disulfiram (Antabuse®) In 1949, disulfiram became the first drug approved to treat alcoholism. The drug works by...
Research in the Laboratory for Integrative Neuroscience (LIN) examines the role of particular molecules in control of actions, acute alcohol intoxication, alcohol seeking behavior, alcohol use disorder and habitual behavior. Another aim of research in LIN is to examine the molecular mechanisms of synaptic modulation and plasticity related to action and habit learning. An important unifying theme of research within...