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National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Genetics of Alcohol Use Disorder

How do genes influence alcohol use disorder? Alcohol use disorder (AUD) often seems to run in families, and we may hear about scientific studies of an “alcoholism gene.” Genetics certainly influence our likelihood of developing AUD, but the story isn’t so simple. Research shows that genes are responsible for about half of the risk for AUD. Therefore, genes alone do...

Directors Reports

NIAAA Director's Report on Institute Activities to the 129th Meeting of the National Advisory Council on Alcohol Abuse and Alcoholism

Contents A. Legislation, Budget, and Policy B. Director's Activities C. NIAAA Staff and Organization D. Press Releases E. Multi-Media Products F. News Media Interactions G. NIAAA Program Annoucement and Request for Applications Information H. NIAAA Research Programs A. Legislation , Budget, and Policy Budget Update FY 2011 In FY 2011, the NIAAA obligated $458.3 million in appropriated money. NIAAA awarded...

News Release

Gene Therapy Technique Reduces Alcohol Consumption in Rats
For Release

Scientists at the U.S. Department of Energy's Brookhaven National Laboratory report in the current Journal of Neurochemistry (Volume 78, Number 5) that they used gene therapy techniques to increase levels of dopamine D2 (DRD2) receptors and reduce drinking in rats previously trained to self-administer alcohol. Panayotis Thanos, Ph.D., Nora Volkow, Ph.D., and colleagues used a partially inactivated virus as a...

News Release

NIH study identifies gene for alcohol preference in rats
For Release

Selectively bred strains of laboratory rats that either prefer or avoid alcohol have been a mainstay of alcohol research for decades. So-called alcohol-preferring rats voluntarily consume much greater amounts of alcohol than do non-preferring rats. Scientists at the National Institutes of Health now report that a specific gene plays an important role in the alcohol-consuming tendencies of both types of...

Directors Reports

NIAAA Director's Report on Institute Activities to the 137th Meeting of the National Advisory Council on Alcohol Abuse and Alcoholism

Table of Contents NIAAA BUDGET DIRECTOR'S ACTIVITIES STAFF TRANSITIONS HONORS & AWARDS NEW RFAs/PAs NOTABLE NIAAA STAFF ACTIVITIES WHAT’S AHEAD NIAAA RESEARCH HIGHLIGHTS NIAAA COMMUNICATIONS, OUTREACH & MEDIA COVERAGE NIAAA BUDGET FY 2014 The NIAAA is currently closing out Fiscal Year (FY) 2014 to coincide with the end of the Fiscal Year calendar, September 30th. As you may recall from...

Directors Reports

NIAAA Directors Report on Institute Activities to the 135th Meeting of the National Advisory Council on Alcohol Abuse and Alcoholism

Table of Contents NIAAA WELCOMES NEW DIRECTOR NIAAA BUDGET DIRECTOR’S ACTIVITIES STAFF TRANSITIONS & AWARDS HONORS & AWARDS NEW RFA’S/PA’S NIAAA COMMUNICATIONS & MEDIA COVERAGE SELECT NIAAA STAFF ACTIVITIES WHAT’S AHEAD NIAAA RESEARCH HIGHLIGHTS NIAAA Welcomes New Director On January 27, 2014, George F. Koob, Ph.D., joined NIH as Director of the National Institute on Alcohol Abuse and Alcoholism. Dr...

News Release

Serotonin Transporter Gene Shown to Influence College Drinking Habits
For Release

Researchers have identified a genetic factor that may predispose young people to harmful drinking habits. A team of scientists interviewed college students about their alcohol consumption and then analyzed their genetic profiles, or genotypes. They found that students who shared a particular variant of the serotonin transporter gene (5HTT) consumed more alcohol per occasion, more often drank expressly to become...

Advisory Council Minutes

Minutes of the 136th Meeting of the NATIONAL ADVISORY COUNCIL ON ALCOHOL ABUSE AND ALCOHOLISM
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DEPARTMENT OF HEALTH AND HUMAN SERVICES NATIONAL INSTITUTES OF HEALTH NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM Minutes of the 136th Meeting of the NATIONAL ADVISORY COUNCIL ON ALCOHOL ABUSE AND ALCOHOLISM June 4–5, 2014 The National Advisory Council on Alcohol Abuse and Alcoholism (NIAAA) convened for its 136th meeting at 5:00 p.m. on June 4, 2014, at NIAAA headquarters...

Directors Reports

NIAAA Director’s Report on Institute Activities to The 119th Meeting of the National Advisory Council on Alcohol Abuse and Alcoholism

CONTENTS A. Legislation, Budget, and Policy B. Director’s Activities C. NIAAA Staff and Organization D. Transdisciplinary Research Activities E. NIAAA Research Programs F. Scientific Meetings G. Outreach H. Multi-Media Products from NIAAA I. What’s Ahead A. Legislation, Budget, and Policy On Monday, June 30, 2008 the President signed into law H.R. 2642, Supplemental Appropriations Act, 2008 netting the NIH an...

Study shows gene editing may hold promise for reversing effects of adolescent binge drinking
This article was first published in NIAAA Spectrum Volume 14, Issue 3. Gene editing could one day help reverse anxiety and excessive drinking caused by adolescent exposure to alcohol, according to a new study in rats supported by the National Institute on Alcohol Abuse and Alcoholism (NIAAA). A team of investigators led by NIAAA grantee Subhash C. Pandey, Ph.D., the...

Directors Reports

NIAAA Director's Report on Institute Activities to the 140th Meeting of the National Advisory Council on Alcohol Abuse and Alcoholism

Table of Contents NIAAA BUDGET LEGISLATIVE NEWS COLLABORATIVE RESEARCH ON ADDICTION AT NIH UPDATE DIRECTOR'S ACTIVITIES STAFF TRANSITIONS HONORS AND AWARDS NEW NOTICE OF FUNDING OPPORTUNITIES NOTABLE NIAAA STAFF ACTIVITIES WHAT'S AHEAD NIH RESEARCH HIGHLIGHTS NIAAA COMMUNICATIONS ACTIVITIES NIAAA BUDGET FY 2015 The NIAAA is currently closing out fiscal year (FY) 2015 to coincide with the end of the federal...

News Release

NIH study identifies gene variant linked to compulsive drinking
For Release
Carrying a gene variant that affects the release of a specific brain protein may put one at greater risk of developing an alcohol use disorder, according to the results of a recent animal study. The study was led by Professor Dorit Ron, PhD, Endowed Chair of Cell Biology of Addiction, Department of Neurology, University of California, San Francisco, and was...

Advisory Council Minutes

Minutes of the 138th Meeting of the NATIONAL ADVISORY COUNCIL ON ALCOHOL ABUSE AND ALCOHOLISM
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DEPARTMENT OF HEALTH AND HUMAN SERVICES NATIONAL INSTITUTES OF HEALTH NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM 138th Meeting of the NATIONAL ADVISORY COUNCIL ON ALCOHOL ABUSE AND ALCOHOLISM February 4 − 5, 2015 The National Advisory Council on Alcohol Abuse and Alcoholism (NIAAA) convened for its 138th meeting at 2:00 p.m. on Wednesday, February 4, 2015, at NIAAA headquarters...

News Release

Sex hormone-sensitive gene complex linked to premenstrual mood disorder
For Release
Dysregulated cellular response to estrogen and progesterone suspected. National Institutes of Health (NIH) researchers have discovered molecular mechanisms that may underlie a woman’s susceptibility to disabling irritability, sadness, and anxiety in the days leading up to her menstrual period. Such premenstrual dysphoric disorder (PMDD) affects 2 to 5 percent of women of reproductive age, whereas less severe premenstrual syndrome (PMS)...

Directors Reports

NIAAA Director’s Report on Institute Activities to The 120th Meeting of the National Advisory Council on Alcohol Abuse and Alcoholism

CONTENTS A. Legislation, Budget, and Policy B. Director’s Activities C. NIAAA Staff and Organization D. Transdisciplinary Research Activities E. Scientific Meetings F. NIAAA Research Programs G. Multi-Media Products from NIAAA H. Outreach I. News Media Interactions J. What’s Ahead K. NIAAA Program Announcement and Request for Applications Information A. Legislation, Budget, and Policy Fiscal Year 2009 On Tuesday, September 30...

Directors Reports

NIAAA Director's Report on Institute Activities to the 151st Meeting of the National Advisory Council on Alcohol Abuse and Alcoholism

Table of Contents NIAAA BUDGET COLLABORATIVE RESEARCH ON ADDICTION AT NIH (CRAN) UPDATE DIRECTOR'S ACTIVITIES STAFF TRANSITIONS HONORS & AWARDS RECENTLY ISSUED NOTICE OF FUNDING OPPORTUNITIES AND NOTICES NOTABLE NIAAA STAFF ACTIVITIES WHAT'S AHEAD NIAAA RESEARCH HIGHLIGHTS NIAAA COMMUNICATIONS ACTIVITIES NIAAA BUDGET Fiscal Year (FY) 2019 On September 28, 2018, the President signed H.R.6157 - Department of Defense and Labor...

Directors Reports

NIAAA Director's Report on Institute Activities to the 132nd Meeting of the National Advisory Council on Alcohol Abuse and Alcoholism

Table of Contents NIAAA DIRECTOR’S NOTE NIAAA BUDGET NIAAA DIRECTOR'S SEARCH DIRECTOR’S ACTIVITIES STAFF TRANSITIONS STAFF HONORS AND EDITORIAL APPOINTMENTS NEW RFA’S/PA’S NIAAA COMMUNICATIONS & MEDIA COVERAGE NOTABLE NIAAA STAFF ACTIVITIES NEW AND UPCOMING PUBLICATIONS WHAT’S AHEAD NIAAA RESEARCH HIGHLIGHTS In Memoriam Daniel W. Hommer (1948 ― 2013) Dr. Daniel W. Hommer, M.D., beloved and respected member of the NIAAA...
Gene Array Technology Center (GATC) for Alcohol Research

GENE EXPRESSION CORE FACILITY for ALCOHOL RESEARCH The NIAAA is supporting a gene microarray technology resource center to assist investigators who are currently conducting, or who have an interest in initiating, gene expression studies that address alcohol-related disorders. The purpose of the Gene Expression Core facility is to provide microarray slides, and technical and bioinformatics services, to investigators for the...

Alcohol Flush Reaction: Does Drinking Alcohol Make Your Face Red?
Some people who drink alcohol experience an unpleasant phenomenon called the alcohol flush reaction. The primary feature of the alcohol flush reaction is a red face—or flush—but it can also be accompanied by hives, nausea, low blood pressure, the worsening of asthma, or an episode of migraine. Of particular significance, the alcohol flush reaction is linked to a higher risk...

News Release

Prevention Program Helps Teens Override a Gene Linked to Risky Behavior
For Release

A family-based prevention program designed to help adolescents avoid substance use and other risky behavior proved especially effective for a group of young teens with a genetic risk factor contributing toward such behavior, according to a new study by researchers at the University of Georgia. The National Institute on Alcohol Abuse and Alcoholism (NIAAA) and the National Institute on Drug...

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