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The National Institutes of Health announced today that enrollment for the Adolescent Brain Cognitive Development (ABCD) Study is now complete and, in early 2019, scientists will have access to baseline data from all ABCD Study participants. There are 11,874 youth, ages 9-10, participating in the study, including 2,100 young people who are twins or triplets. All will be followed through...
In recent years, a class of small molecules known as microRNAs have been found to play an important role in regulating gene products in most animal and plant species. A new study now indicates that microRNA may influence the development of alcohol tolerance, a hallmark of alcohol abuse and dependence. Researchers supported by the National Institute on Alcohol Abuse and...
You may be familiar with how doctors use pictures from magnetic resonance imaging machines, better known as MRIs, to diagnose injuries and other health problems. But did you know that NIAAA scientists have another technology that harnesses the power of strong magnets to study receptors in the brain that could be targets for alcohol therapies? NIAAA’s Intramural Section on Nuclear...
The latest article from Alcohol Research Current Reviews explores co-occurrence of alcohol use disorder and depression. Alcohol use disorder (AUD) and depressive disorders are among the most prevalent psychiatric disorders and co-occur more often than expected by chance. Studies have indicated that the co-occurrence of AUD and depressive disorders is associated with greater severity and worse prognosis for both disorders...
A team of alcohol researchers led by Jack Stapleton, M.D., of the Department of Internal Medicine, University of Iowa College of Medicine and the Iowa City Veterans Affairs Medical Center, report in the September 6 New England Journal of Medicine , Volume 345, 2001 ( Effect of co-infection with GB virus type C (Hepatitis G Virus) on survival of HIV-infected...
Scientists at the National Institutes of Health’s (NIH) National Institute on Alcohol Abuse and Alcoholism (NIAAA) have identified a previously unknown gene variant that doubles an individual’s risk for obsessive-compulsive disorder (OCD). The new functional variant, or allele, is a component of the serotonin transporter gene ( SERT), site of action for the selective serotonin reuptake inhibitors (SSRIs) that are...
Data from a recent epidemiologic survey of more than 43,000 U.S. adults show that antisocial syndromes-marked by little concern for the rights of others and violations of age-appropriate societal rules-are more common among people with substance abuse disorders than those without these disorders. The study by researchers from the National Institute on Drug Abuse (NIDA) and National Institute on Alcohol...
Endorsement and Liability Disclaimer The National Institute on Alcohol Abuse and Alcoholism (NIAAA) does not endorse or recommend any commercial products, processes, or services. The information on NIAAA's Web site may not be used for advertising or product endorsement purposes. The NIAAA website provides links to other Internet sites for informational purposes only. When users select a link to an...
Note: space is limited to 50 participants; please RSVP by May 1, 2015 to M. Reilly at reillymt@mail.nih.gov . Purpose: to bring together (Library of Integrated Network-based Cellular Signatures) LINCS 1 scientists and scientists from the alcohol research community to explore how LINCS resources can facilitate identification of druggable targets and novel and/or repurposed compounds for the treatment of alcohol...
New research by NIAAA scientists shows that an experimental drug that targets molecular sites in the liver and other tissues without acting on identical sites in the brain, holds promise as an effective treatment for obesity and its complications. In the July 26, 2012 issue of the journal Cell Metabolism, researchers led by NIAAA Scientific Director George Kunos, M.D., Ph.D...
On Friday, June 7 the Interagency Coordinating Committee on Fetal Alcohol Spectrum Disorders (ICCFASD) will meet. This meeting is open to the public, who can attend in person or watch the videocast. View the meeting agenda In person attendance (on-site guest parking is available): National Institute on Alcohol Abuse and Alcoholism 6700B Rockledge Drive, First Floor Conference Center Rockville, Maryland...
Voluntary movements involve the coordinated activation of two brain pathways that connect parts of deep brain structures called the basal ganglia, according to a study in mice by researchers at the National Institute on Alcohol Abuse and Alcoholism (NIAAA), part of the National Institutes of Health. The findings, which challenge the classical view of basal ganglia function, were published online...
Our society is hotly debating the question of whether to decriminalize or even legalize the use of marijuana, and even though pro-legalization voices do not advocate making the drug legal for minors, it is likely that adolescents in more and more states will have easier access to this drug in coming years. At the same time, we are seeing new...
Changes to genetic material in the brain may help induce the anxiety that is characteristic of alcohol withdrawal, according to a new study supported by the National Institute on Alcohol Abuse and Alcoholism (NIAAA), part of the National Institutes of Health (NIH). The finding points to possible therapies to prevent withdrawal-related anxiety, a driving force behind alcohol use among dependent...
