National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Investigators at the University of Texas Health Science Center at San Antonio report in the lead article in today's Journal of the American Medical Association (Volume 284, Number 8) that the medication ondansetron may be an effective therapy for patients with early-onset alcohol dependence (alcoholism). Ondansetron appears to work by acting on serotonin, one of the brain's many neurotransmitters. The...
First prize winner will be awarded $200,000 In the search for a wearable or otherwise discreet device capable of measuring blood alcohol levels in real time, the National Institute on Alcohol Abuse and Alcoholism (NIAAA) has issued the Wearable Alcohol Biosensor Challenge. The wearable biosensor will aid researchers, clinicians, therapists and individuals by providing more accurate data on how much...
Members of the Committee, thank you for your concern about alcohol, drug, and mental health problems, issues that rank very high in their impact on public health and on the Nation. I thank my distinguished colleagues for their contributions in these areas and for sharing in our discussion today. I am Dr. Ting-Kai Li, Director of the National Institute on...
Muscle weakness from long-term alcoholism may stem from an inability of mitochondria, the powerhouses of cells, to self-repair, according to a study funded by the National Institutes of Health. In research conducted with rats, scientists found evidence that chronic heavy alcohol use affects a gene involved in mitochondrial repair and muscle regeneration. “The finding gives insight into why chronic heavy...
NIH-funded multi-site clinical trial suggests that smokers may also benefit A new medication that targets part of the brain’s stress system may help reduce alcohol use in people with alcohol use disorder (AUD), according to a new study by researchers at the National Institute on Alcohol Abuse and Alcoholism (NIAAA), part of the National Institutes of Health. “Medications have become...
A brain circuit that underlies feelings of stress and anxiety shows promise as a new therapeutic target for alcoholism, according to new studies by researchers at the National Institute on Alcohol Abuse and Alcoholism (NIAAA), part of the National Institutes of Health (NIH). In preclinical and clinical studies currently reported online in Science Express, NIAAA Clinical Director Markus Heilig, M.D...
Drinking alcoholic beverages has been linked to an increased risk of upper gastrointestinal cancer and other types of cancer. Researchers looking for the potential biochemical basis for this link have focused on acetaldehyde, a suspected carcinogen formed as the body metabolizes alcohol. In the journal Nucleic Acids Research (vol. 33, num. 11), scientists from the National Institute on Alcohol Abuse...
Interventions to reduce anxiety and depression may help prevent relapse in individuals with chronic pain who are recovering from alcohol use disorder (AUD). This conclusion comes from a recent study in which investigators reanalyzed data collected from people with chronic pain who participated in one of two major clinical trials on alcohol treatment, one in the United States and one...