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National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Young Drinkers Risk Slowing Down Brain Power

Drinking may harm adolescents' ability to concentrate and to understand spatial relationships. A recent study led by Susan Tapert at the University of California, San Diego compared the standardized test scores of 76 12 to 14 year old kids with their scores after about three years. At the three-year follow-up, 36 of the kids had begun drinking at moderate to...

Advisory Council Minutes

National Advisory Council Meeting - June 4-5, 2008
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NATIONAL ADVISORY COUNCIL ON ALCOHOL ABUSE AND ALCOHOLISM Summary of the 118th Meeting June 4-5, 2008 The National Advisory Council on Alcohol Abuse and Alcoholism convened for its 118th meeting at 5:30 p.m. on June 4, 2008, at the FishersLaneConferenceCenter in Rockville, Maryland, in a closed session. Dr. Abraham Bautista presided over the closed review of grant applications. Dr. Ting-Kai...

Glosario
Años de vida ajustados por discapacidad ( disability-adjusted life years ): Una medida de los años de vida perdidos o vividos con menos de una salud plena. Consumo de alcohol en altas cantidades ( high-intensity drinking ): El consumo de alcohol a niveles que son dos o más veces superiores a los umbrales de consumo excesivo y peligroso de alcohol...
Join a Study
Browse Selected Studies: Study#14-AA-0181: NIAAA Natural History Protocol Study#16-AA-0037: A Study Drug’s Effects on Brain Receptors and Alcohol Self-Administration Study#08-AA-0178: Developing a Human Laboratory Model for Alcohol Self-Administration Study#17-AA-0171: Nicotinic Receptor Genetic Variation and Alcohol Reward Study#000036-AA: Alirocumab in Non-treatment Seeking Heavy Drinkers Study#14-AA-0066: Task Development Study#18-AA-0098: Socioemotional Processing associated with Alcohol Use Disorder & Craving Control Using Neurofeedback Study#20-AA-0057...
NIH HEAL Initiative Concept: Developing an Evidence Base for OUD-AUD Interventions
Mark Egli, Ph.D. May 09, 2023 Background At least 30% of people with OUD also have AUD. Research projects dedicated to OUD treatment and prevention do not exclude subjects who drink, but seldom explicitly recruit subjects with AUD. Reciprocal relationships between opioid use and alcohol use sometimes seen in treatment contexts such that reduced opioid misuse and opioid agonist therapy...
Medications Development Program

Treatment for alcohol use disorder (AUD) includes behavioral treatments such as mutual support groups and individual therapy, as well as pharmaceutical treatments. Often these are used in combination. Currently, there are three Food and Drug Administration (FDA)-approved medications for the treatment of AUD: Disulfiram (Antabuse®) In 1949, disulfiram became the first drug approved to treat alcoholism. The drug works by...

Study Highlights Importance of Positive Alcohol Responses for Future Alcohol Problems

Some people experience the initial effects of alcohol as stimulating and euphoric, while others experience mostly unpleasant sedative effects. How individuals’ immediate responses to alcohol influence their future drinking behavior has been an active area of scientific research. One theory holds that people who have a low level of positive response to alcohol and who also are less sensitive to...

Alcohol and Pregnancy in the United States
According to the Behavioral Risk Factor Surveillance Survey (BRFSS)—a survey of more than 400,000 people by the U.S. Centers for Disease Control and Prevention—during 2018–2020, nearly 14% of pregnant people ages 18 to 49 reported current drinking. 1 Also according to BRFSS, during 2018–2020, about 5% of pregnant people ages 18 to 49 reported binge drinking in the past 30...

News Release

NIH study finds doctors miss many alcohol screening opportunities
For Release

Physicians often fail to counsel their young adult patients about excessive alcohol use, according to a study led by the National Institute on Alcohol Abuse and Alcoholism (NIAAA), part of the National Institutes of Health. NIAAA guidelines for low risk drinking call for men to drink no more than four drinks in a day and no more than 14 drinks...

Behavioral and Drug Therapy Together Help Treat Alcoholism

A new analysis has shown that combined behavioral intervention (CBI), counseling that integrates cognitive-behavioral therapy, motivational enhancement, and techniques to enhance mutual help group participation, used alone in conjunction with naltrexone, a drug approved to help treat alcoholism, can reduce drinking in alcohol-dependent individuals. In this reanalysis of data from the COMBINE Study—the largest pharmacotherapy trial for alcoholism in the...

News Release

NIH develops improved mouse model of alcoholic liver disease
For Release
Scientists may be better able to study how heavy drinking damages the liver using a new mouse model of alcohol drinking and disease developed by researchers from the National Institute on Alcohol Abuse and Alcoholism (NIAAA), part of the National Institutes of Health. The model incorporates chronic and binge drinking patterns to more closely approximate alcoholic liver disease in humans...
Levetiracetam Study
Data Access Policy, Application and Agreement NIAAA Protocol NCIG 002: A Multisite Double-Blind, Placebo-Controlled Trial of Levetiracetam Extended-Release in Very Heavy-Drinking Alcohol-Dependent Patients Description This multisite clinical trial evaluated the efficacy and safety of levetiracetam XR, for the treatment of alcohol use disorder (AUD). Study Details Sponsor: The National Institute on Alcohol Abuse and Alcoholism’s Clinical Investigations Group (NCIG) NCT #...

Announcement

New Issue of NIAAA Spectrum is Now Available!
NIAAA Spectrum is the National Institute on Alcohol Abuse and Alcoholism's (NIAAA) triannual webzine. With engaging feature articles, short news updates, and colorful graphics, NIAAA Spectrum offers accessible and relevant information on NIAAA and the alcohol research field. The latest issue is now available . In This Issue Advances in Understanding and Addressing Underage Drinking Combating underage drinking is a...

News Release

Alcohol Researchers Prove Success with Primary Care Interventions
For Release

Michael Fleming, M.D., M.P.H., and colleagues at the University of Wisconsin Medical School in Madison report in the April 2 Journal of the American Medical Association results from Project TrEAT (Trial for Early Alcohol Treatment), the first large U.S. clinical trial to test the effectiveness of brief physician advice for intervening with nondependent problem drinkers. Supported by a grant from...

Alcohol Screening and Brief Intervention for Youth: A Practitioner's Guide
If you manage the health and well-being of 9- to 18-year-olds, this Guide is for you. “Alcohol Screening and Brief Intervention for Youth: A Practitioner’s Guide” is designed to help health care professionals quickly identify youth at risk for alcohol-related problems. NIAAA developed the Guide and Pocket Guide in collaboration with a team of underage drinking researchers and clinical specialists...
Alcohol Epidemiologic Data Directory 2022
Print PDF TABLE OF CONTENTS INTRODUCTION Section 1: National Health and Alcohol Data Sets. Behavioral Risk Factor Surveillance System (BRFSS)—1984–2020, Annually. Collaborative Initiative on Fetal Alcohol Spectrum Disorders (CIFASD)—2003–2007, 2007–2012, 2012–2017. Collaborative Study on the Genetics of Alcoholism (COGA)—1991–2016, Ongoing. Coronary Artery Risk Development in Young Adults (CARDIA)—1985–1986, 1987–1988, 1990–1991, 1992–1993, 1995–1996, 2000–2001, 2005–2006, 2010–2011, and 2015–2016. Drug Abuse Warning...

News Release

NIH findings link aldosterone with alcohol use disorder
For Release
A new study led by scientists at the National Institute on Alcohol Abuse and Alcoholism (NIAAA), part of the National Institutes of Health, demonstrates that aldosterone, a hormone produced in the adrenal glands, may contribute to alcohol use disorder (AUD). The novel research, conducted in collaboration with a team of investigators in the United States and Europe, appears in the...

News Release

NIAAA honors Jonathan Gibralter with Senator Harold Hughes Award
For Release
Jonathan Gibralter, Ph.D., president of Frostburg State University (FSU), received the Senator Harold Hughes Memorial Award today from the National Institute on Alcohol Abuse and Alcoholism (NIAAA), part of the National Institutes of Health. NIAAA Director George Koob, Ph.D., announced his selection during the 139 th meeting of the National Advisory Council on Alcohol Abuse and Alcoholism. The Hughes Award...
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